Publication details

Structure-functional study of lectins: key players in a fight between host and pathogen

Authors

HOUSER Josef MALINOVSKÁ Lenka FUJDIAROVÁ Eva JANČAŘÍKOVÁ Gita KOMÁREK Jan HOLKOVÁ Jitka WIMMEROVÁ Michaela

Year of publication 2019
Type Conference abstract
MU Faculty or unit

Central European Institute of Technology

Citation
Description Lectins are proteins that reversibly interact with sugars. They role range from glycoprotein folding, through cell maturation to host-pathogen recognition. To describe a lectin we apply a broad range of biophysical techniques. In addition to analysis of its affinity and specificity, we also determine lectin structures and combine our findings with in silico modelling. Our results may find application in basic research, medicine as well as biotechnologies.
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