Publication details
Atypický hemolyticko-uremický syndrom komplikovaný infekcí enterohemoragickou Escherichia coli O157:H7
| Title in English | Atypical hemolytic uremic syndrome complicated by infection with enterohemorrhagic Escherichia coli O157:H7 |
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| Authors | |
| Year of publication | 2019 |
| Type | Article in Periodical |
| Magazine / Source | Zprávy Centra Epidemiologie a Mikrobiologie |
| MU Faculty or unit | |
| Citation | |
| Keywords | Enterohemorrhagic Escherichia coli (EHEC), E.coli O157:H7, hemolytic uremic syndrome (HUS), D+ HUS, atypical HUS, laboratory diagnosis, epidemiological investigation |
| Description | The authors present a case of severe diarrhea-positive hemolytic uremic syndrome (D+HUS) in a 4,5-year-old boy associated with infection by enterohemorrhagic Escherichia coli (EHEC) O157:H7 producing Shiga toxin 2c. The patient was admitted to the hospital with atypical HUS (aHUS) based on CD46/MCP (membrane cofactor protein) deficiency/mutation. This case thus represents a rare coincidence of aHUS and EHEC O157:H7 infection. |