Publication details

Efficacy of new cephalosporins in treatment of multidrug-resistant strains of gram-negative bacteria in burn patients



Year of publication 2019
Type Article in Periodical
Magazine / Source Burns
MU Faculty or unit

Faculty of Medicine

Keywords multidrug-resistant strains; gram-negative bacteria; cephalosporins
Description Burn patients are confronted with a variety of potentiallypathogenic microorganisms every day. Although increasingprevalence of micromycetal infections has been observed,especially in the last decade, bacteria remain the dominantpathogens in the etiology of infectious complications in thesepatients. In particular, gram-negative bacteria have a signifi-cant impact on mortality and morbidity of burn patients(Enterobacteriaceae, Pseudomonas aeruginosa). One possibleexplanation is a dramatic increase in resistance of thesepathogens (high prevalence of multidrug resistant–MDR–bacterial strains) and the second possibility is an insufficientamount of available and effective antibiotics (especiallyagainst carbapenem-resistantEnterobacteriaceae—CRE).

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