Publication details

Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs

Authors

HANÁKOVÁ Kateřina BERNATÍK Ondřej KRAVEC Marek MICKA Miroslav KUMAR Jitender HARNOŠ Jakub OVESNÁ Petra PACLÍKOVÁ Petra RÁDSETOULAL Matěj POTĚŠIL David TRIPSIANES Konstantinos ČAJÁNEK Lukáš ZDRÁHAL Zbyněk BRYJA Vítězslav

Year of publication 2019
Type Article in Periodical
Magazine / Source Cell Communication and Signaling
MU Faculty or unit

Faculty of Science

Citation
Web https://biosignaling.biomedcentral.com/articles/10.1186/s12964-019-0470-z
Doi http://dx.doi.org/10.1186/s12964-019-0470-z
Keywords CK1; Dishevelled; DVL3; Kinase; Mass spectrometry; NEK2; Phosphorylation; TTBK2; Wnt
Description Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation generates complex barcodes underlying diverse DVL3 functions.
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