Publication details
Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode
| Authors | |
|---|---|
| Year of publication | 2018 |
| Type | Article in Proceedings |
| Conference | PROCEEDINGS OF THE INTERNATIONAL CONFERENCE MODERN ELECTROCHEMICAL METHODS XXXVIII |
| MU Faculty or unit | |
| Citation | |
| Web | https://asep.lib.cas.cz/arl-cav/cs/detail-cav_un_epca-0506554-Study-of-Synthetic-Oligonacleotides-Containing-Guanine-by-Voltammetry-on-a-Graphite-Electrode/ |
| Keywords | Oligonucleotides; Pyrolytic graphite electrode; Linear sweep voltammetry |
| Description | Electrochemical oxidation of specifically designed DNA hexamers containing guanine has been studied in aqueous acetate buffet (pH 5) at a pyrolytic graphite electrode (PGE) by linear sweep voltammetry (LSV) Influence of the oligonucleotide composition and concentration was investigated It seems that short oligonucleotides containing guanine produce oxidation signals. which are sensitive to their structural properties Simple electrochemical techniques us may be useful tool for monitoring of structural changes of DNA. |