Publication details

Lurasidon v léčbě pacienta se schizofrenií a metabolickým syndromem

Title in English Lurasidone in the treatment of a patient with schizophrenia and metabolic syndrome
Authors

USTOHAL Libor HOŘÍNKOVÁ Jana

Year of publication 2020
Type Article in Periodical
Magazine / Source Česká a slovenská psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.cspsychiatr.cz/detail.php?stat=1353
Keywords lurasidone; metabolic syndrome; schizophrenia; side-effects; treatment;
Description The case study presents successful change of antipsychotic medication from olanzapine to lurasidone in a patient with schizophrenia and metabolic syndrome; to an antipsychotic medication with minimal metabolic side-effects which is newly available in our country. This patient did not tolerate risperidone because of side-effects joined to hyperprolactinemia, quetiapine was not effective enough, the change to aripiprazole was not successful, although the combination with it and later with cariprazine made it possible to temporarily decrease olanzapine dosage. Finally, the initiation of lurasidone made possible to stop olanzapine without worsening of patient’s state. On the contrary, his depressive symptomatology slightly improved. The cross-titration was slow, lasting almost three weeks.

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