Publication details

Použití dermální náhrady v rekonstrukci hlubokých defektů měkkých tkání nejen termální etiologie

Title in English The use of dermal substitute in the reconstruction of deep soft tissue defects not only of thermal etiology
Authors

LIPOVÝ Břetislav KNOZ Martin HOLOUBEK Jakub KEMPNÝ Tomáš BOŘILOVÁ LINHARTOVÁ Petra

Year of publication 2020
Type Article in Periodical
Magazine / Source Česká dermatovenerologie
MU Faculty or unit

Faculty of Medicine

Citation
Web http://referatovyvyber.cz/dermatovenerologie/images/flippingbook/RVD-2-2020/RVD-2-2020.pdf
Keywords dermal substitutes; burns; soft-tissue defects
Description The classic strategy to deep dermal skin defect closing with an autologous dermo-epidermal graft is still the only one option in a comprehensive solution to this problem in many sites today. Despite the fact that it is a relatively simple and fast procedure, the absence of dermis creates chance for chaotic activity of fibroblasts with subsequent uncoordinated deposition of collagen fibrils. In this way, pathological types of scars are formed, which affect the unsatisfactory functional and aesthetic result. Efforts to improve the quality of life after skin trauma have introduced a number of dermal substitutes into relatively common clinical practice. The review article discusses the use of the Matriderm® dermal substitute with a demonstration of clinical applications.

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