Publication details

Asistovaná reprodukce u mužů s Klinefelterovým syndromem

Title in English Assisted reproduction in patients with Klinefelter syndrome
Authors

CRHA Karel JEŠETA Michal PILKA R. KAŠÍK Marek MEKIŇOVÁ Lenka VODICKA J. CRHA Tomáš

Year of publication 2022
Type Article in Periodical
Magazine / Source CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.cs-gynekologie.cz/en/journals/czech-gynaecology/2022-2-5/assisted-reproduction-in-patients-with-klinefelter-syndrome-130701?hl=cs
Doi http://dx.doi.org/10.48095/cccg2022133
Keywords disorders of spermatogenesis; male sterility; Klinefelter syndrome; assisted reproduction; aneuploidy; genetic testing
Description Objective: The goal of this article is to present the current knowledge of Klinefelter syndrome and its impact on male reproductive function as well as the current treatment options. Methods: PubMed/Medline, WoS and Scopus were searched for articles indexed until November 2021. Text: Klinefelter syndrome is a chromosomal aberration with an additional X chromosome in males. This may adversely affect testicular growth and spermatogenesis, thus resulting in male infertility. Recently, new knowledge has appeared about the treatment of male infertility. Conclusion: Interdisciplinary approach enables early dia­gnosis and treatment of patients with Klinefelter syndrome. Assisted reproductive technology is essential for infertility treatment in patients with Klinefelter syndrome.

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