Publication details
Nekrobiotický xantogranulom a monoklonální gamapatie
| Title in English | Necrobiotic xanthogranuloma and monoclonal gammopathy |
|---|---|
| Authors | |
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie, Olomouc, Solen. |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.36290/xon.2022.056 |
| Description | Necrobiotic xanthogranuloma is a progressive and destructive disease associated with paraproteinemia, multiple organ involvement, and an increased risk of developing lymphoproliferative malignancy, such as multiple myeloma, chronic lymphocytic leukemia, or Hodgkin and non-Hodgkin lymphoma. The present article describes a complicated case of a female patient diagnosed with multiple myeloma and necrobiotic xanthogranuloma whose serious health complications were not typical for the diagnosis of multiple myeloma. A thorough diagnostic algorithm and multidisciplinary cooperation of various experts led to the definitive diagnosis. The article also includes a description of the treatment strategy using combination therapy of daratumumab plus lenalidomide and dexamethasone with intravenous administration of immunoglobulins. |