Publication details
1. místo v Biologické sekci Nadnárodního kola studentské vědecké konference
| Authors | |
|---|---|
| Year of publication | 2022 |
| MU Faculty or unit | |
| Citation | |
| Description | Our research studied the biological activity of new derivates of hydroxamic acids as potential histone deacetylase inhibitors designed and synthesized by the Department of Chemical Drugs, Faculty of Pharmacy, Masaryk University. In particular, our study was focused on evaluating their potential to affect histone acetylation and to induce apoptosis in the monocytic leukemia cell line compared with vorinostat. |
| Related projects: |