Publication details
Staining Tissues with Basic Blue7: A New Dual-Polarity Matrix for MALDI Mass Spectrometry Imaging
| Authors | |
|---|---|
| Year of publication | 2025 |
| Type | Article in Periodical |
| Magazine / Source | ANALYTICAL CHEMISTRY |
| MU Faculty or unit | |
| Citation | |
| web | https://pubs.acs.org/doi/10.1021/acs.analchem.4c05244 |
| Doi | http://dx.doi.org/10.1021/acs.analchem.4c05244 |
| Keywords | MALDI matrix; Basic Blue 7; dye; staining; mass spectrometry imaging; MALDI MSI; sample preparation; lipids |
| Description | A new dye-based matrix (Basic Blue 7) for MALDI mass spectrometry imaging has been discovered. Basic Blue 7 allows a new method of application on samples – tissue staining by sample immersion in dye solution. This protocol allows to record high-quality MALDI MS images in both positive and negative modes, comparable to those obtained with classical matrices 2,5-dihydroxybenzoic acid and 1,5-diaminonaphthalene. |
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