Publication details
Nízkoobjemové postižení regionálních lymfatických uzlin u karcinomu endometria - 2024 update
| Title in English | Low-volume regional lymph node metastasis in endometrial cancer-2024 update |
|---|---|
| Authors | |
| Year of publication | 2025 |
| Type | Article in Periodical |
| Magazine / Source | Ceska Gynekologie-Czech Gynaecology |
| MU Faculty or unit | |
| Citation | |
| web | https://redakce.carecomm.cz/cgyn/article/view/2612 |
| Doi | https://doi.org/10.48095/cccg2025158 |
| Keywords | low-volume metastasis; endometrial cancer; ultrastaging; isolated tumor cells; micrometastases; sentinel lymph node |
| Description | Due to the implementation of sentinel lymph node ultrastaging, the prevalence of isolated tumor cells and micrometastases have increased. This literature review comprises of articles published between January 2019 and September 2024 aiming at low-volume metastases in regional lymph nodes, their prognosis, and links to molecular classifi cation. Micrometastases are currently considered as having metastatic lymph node involvement; however, they have a better prognosis than macrometastases. Accordingly, therapy is tailored. In contrast, isolated tumor cell presence is not considered metastatic involvement according to International Federation of Gynecology and Obstetrics (FIGO) 2023 staging and does not aff ect the therapeutic procedure because their signifi cant prognostic importance has not been proven so far. |