Publication details

Ultra fast oscillations in the human brain and their functional significance

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Authors

BRÁZDIL Milan TRÁVNÍČEK Vojtěch CUROT Jonathan PAIL Martin SŁUŻEWSKA-NIEDŹWIEDŹ Monika ROMAN Robert BARBEAU Filip PlešingerEmmanuel KUCEWICZ Michal KLIMEŠ Petr CIMBÁLNÍK Jan JURÁK Pavel STACEY William C WORRELL Gregory A

Year of publication 2025
Type Article in Periodical (without peer review)
MU Faculty or unit

Faculty of Medicine

Citation
Description Human brain cell assemblies fire electrical impulses up to very high frequencies, which limit is not yet known. Using advanced intracranial microEEG recordings in a cohort of epileptic patients, we newly identified short-lasting oscillations in frequencies between 2 and 8 kHz. These ultra fast oscillations were consistently and locally detected in epileptic hippocampi but were extremely rare in non-epileptic brain tissue. The discovered electrophysiological phenomena thus may reflect neuronal hyperexcitability.
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