Publication details
A newly developed cobalt(II) complex derived from a thiourea derivative and assessment of its potential bioapplicability against plant root pathogens
| Authors | |
|---|---|
| Year of publication | 2025 |
| Type | Article in Periodical |
| Magazine / Source | JOURNAL OF COORDINATION CHEMISTRY |
| MU Faculty or unit | |
| Citation | |
| web | https://www.tandfonline.com/doi/full/10.1080/00958972.2025.2583368 |
| Doi | https://doi.org/10.1080/00958972.2025.2583368 |
| Keywords | Monoclinic packing; sulfur ligand; transition metal; phytopathogen; wheat germination |
| Description | via an addition reaction, a tetrahedral cobalt(II) complex with the asymmetric ligand 1-(2,5-dimethylphenyl)-3-phenylthiourea (L) was synthesized. Crystal structure of the complex, [CoL2Cl2], demonstrated a monoclinic system packing and coordination of the divalent cobalt ion with S atoms of two thiourea ligand molecules and two chlorine atoms. Fusarium species are very destructive phytopathogens, causing considerable economic loss. Drawbacks of organic antifungals include their poor solubility, instability and limited bioavailability. Environmental accumulation and negative effects on people's health are results of their extensive use. The complex [CoL2Cl2], comparing with its precursors, offered higher inhibitions in plates of three Fusarium phytopathogens, i.e. Fusarium lateritium, Fusarium oxysporum, and Fusarium solani. [CoL2Cl2] (150 mu g/ml) inhibited F. oxysporum, F. solani, and F. lateritium by 28-38 mm, but 1-(2,5-dimethylphenyl)-3-phenylthiourea and cobalt(II) chloride hexahydrate inhibited these fungi by 7-8.5 and 7.5-24.5 mm, respectively. In the presence of [CoL2Cl2] (150 mu g/ml), the percent pathogenicity to wheat seeds by F. oxysporum and F. lateritium was brought to zero (20% by F. solani). Phytotoxicity action of [CoL2Cl2], cobalt(II) chloride hexahydrate, and 1-(2,5-dimethylphenyl)-3-phenylthiourea (150 mu g/ml) on wheat seed germination was weak, reducing the optimal germination percentage (100% for control) to 83.3, 76.7, and 90%, respectively. |