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Standardization of methods for characterization of mechanical properties of soft samples at nanoscale

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BRÁZDILOVÁ Barbora PŘIBYL Jan

Year of publication 2025
Type Conference abstract
MU Faculty or unit

Central European Institute of Technology

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Description Soft materials, including biopolymers, hydrogels, and biological tissues, exhibit highly dynamic and unique mechanical behaviors. Their viscoelastic properties, structural heterogenity, and sensitivity to external factors lead to challenges in precise evaluation. A deeper understanding of these properties at the nanoscale is crucial for various fields, including biomedical engineering, materials science, and nanotechnology, as it can lead to advancements in biomaterials and tissue engineering. This presentation presents measurement techniques, particularly atomic force microscopy (AFM) and nanoindentation and how standardization improve the reproducibility and reliability of the assessment of soft materials mechanical properties. To validate the robustness and accuracy of these standardized techniques, both intra-laboratory and inter-laboratory comparisons will be presented. By improving measurement accuracy and reproducibility, this research aims to provide a strong basis for future studies on soft material mechanics, facilitating their integration into advanced biomechanical and nanotechnological applications. This work contributes to international scientific collaboration through participation in the COST MecaNano consortium.
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