Publication details
Biologická a farmakologická aktivita lignanů
| Title in English | The Biological and Pharmacological Activity of Lignans |
|---|---|
| Authors | |
| Year of publication | 2000 |
| Type | Article in Periodical |
| Magazine / Source | Chemické listy |
| MU Faculty or unit | |
| Citation | |
| Field | Biochemistry |
| Keywords | lignany; biologická aktivita |
| Description | Lignans are secondary plant metabolites consisting of two phenylpropane units. Their antineoplastic, cardiovascular and antioxidant activities are discused in the review. The podophyllotoxin derivatives etoposide and teniposide are used in medical practice as cytostatics. Enterolactone and enterodiol were identified in serum and urine of mammalians. They are formed as metabolic products of intestinal microflora from plant precursors, acting in the organism as phytoestrogens and probably preventing some types of cancer. |