Publication details
Dlouhodobá prognóza polyneuromyopatie kritického stavu
| Title in English | Lon-term prognosis of critical illness polyneuromyopathy |
|---|---|
| Authors | |
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | Anesteziologie & Intenzivní medicína |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | critical illness; polyneuropathy; myopathy; multiple orga failure; systemic inflammatory response syndrome |
| Description | Objective: To evaluate the long-term outcome and prognosis in critically ill patients with neuromuscular complications. Desing: Prospective clinical study. Material and Methods: Seventy-nine critically ill patients were enrolled and forty-eight completed a one-month follow-up. Selected clinical parameters were prospectively evaluated over a 28-day period. Electrophysiological studies were performed during the first week and at the end of the follow-up in order to detect signs of critical illness polyneuromyopathy (CIPM). Clinical features and outcomes were evaluated six months after the onset of a critical illness in eleven patients with CIPM. Results: Electrophysiological signs of CIPM were detected in twenty-seven patients (56.3%). Clinical manifestation with the onset of profound flaccid paralysis occured in seven cases (14.6%), four of them with difficult weaning from mechanical ventilation. Sixteen patients with CIPM died during six months after the onset of critical illness - moratility rate of 59.3%. Among survivors, 7 patients (63.6%) were independent in their daily activities (Barthel Index 60 or more). Conclusions: Despite a severe initial motor deficit, recovery from CIPM may be in most cases partial or complete within 6-month period, with no significant impairment of patients self-sufficiency and quality of life. |
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