Publication details
A gender-specific association between a novel A5495G variant in the endothelial nitrix oxide synthase gene (NOS3) and respiratory allergy in the Czech population
| Authors | |
|---|---|
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | Eur.Respir.J. |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | NOS; gene; polymorphism; gender; association |
| Description | Several studies suggest that abnormalities in nitrix oxide (NO) synthesis may contribute to the development of pulmonary diseases. We recently identified a novel variant within intron 4 of the NOS3 gene: A to G conversion at nucleotide position 5495. We have, therefore, performed a case-control study to investigate a plausible association between this polymorphism in the NOS3 gene and respiratory allergic diseases. |
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