Publication details

Modelling the distribution of [Ca2+] within the cardiac t-tubule: effects of Ca2+ current distribution and changes in extracellular [Ca2+]

Authors

ŠIMURDA Jií PÁSEK Michal CHRISTÉ Georges ŠIMURDOVÁ Milena

Year of publication 2004
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description To calculate the spatial and temporal distribution of [Ca2+] within the transverse tubules (t-tubules) of cardiac myocytes, we have developed a model described by partial differential equations. Ca2+ diffusion, and Ca2+ binding at the t-tubule membrane and/or in the t-tubule lumen were modelled for cylindrical (254 nm diameter) t-tubules of finite length.
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