Publication details

Correlation of Expression of Ki-67, EGFR, c-erbB-2,MMP-9, p53, bcl-2, CD34 and Cell Cycle Analysis with Survival in Head and Neck Squamous Cell Cancer

Authors

SMILEK Pavel DUŠEK Ladislav VESELÝ Karel ROTTENBERG Jan KOSTŘICA Rom

Year of publication 2006
Type Article in Periodical
Magazine / Source Journal of Experimental & Clinical Cancer Research
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords Head and neck cancer; mitotic index;bcl-2;DNA cytometry
Description The analysis of the set of 217 patients suffering from head and neck carcinoma was done. Cytokinetic parameters strongly correlated with grade score.Positivity in bcl-2, and MMP-9 was related to OS. Positivity of EGFR, C-erbB-2, CD34, p53 did not reached statistically significant value in association to EFS or OS.
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