Publication details

C-Geranyl Compounds from <i>Paulownia tomentosa</i> Fruits

Authors

ŠMEJKAL Karel GRYCOVÁ Lenka MAREK Radek LEMIERE Filip JANKOVSKÁ Dagmar FOREJTNÍKOVÁ Hana VANČO Ján SUCHÝ Václav

Year of publication 2007
Type Article in Periodical
Magazine / Source Journal of Natural Products
MU Faculty or unit

Faculty of Science

Citation
Web DOI: 10.1021/np070063w
Doi http://dx.doi.org/10.1021/np070063w
Field Analytic chemistry
Keywords flavonoid; geranyl; natural product; NMR
Description Five geranylflavonoids, one prenylated flavonoid, and a simple flavanone were isolated from an ethanolic extract of Paulownia tomentosa fruit. Tomentodiplacol (1), 3-O-methyl-5-methoxydiplacol (2), 6-isopentenyl-3-O-methyltaxifolin (3), and dihydrotricin (4) are reported from a natural source for the first time and 3-O-methyldiplacone (6) for the first time from the genus Paulownia. The structures of the compounds were determined by mass spectrometry, including HR-MS, and by 1D and 2D NMR spectroscopy. The cytotoxicity and DPPH (2,2-diphenyl-1-picrylhydrazyl) quenching activity of some of these compounds were tested, with diplacone proving to be the best antioxidant, though the most cytotoxic compound.
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