Behavioural sensitization to methamphetamine is associated with cannabinoid CB1 receptors downregulation in the rat brain VTA

• Authors: ŠULCOVÁ Alexandra; DUBOVÝ Petr; KUČEROVÁ Jana
• Year of publication: 2007
• Type: Article in Periodical
• Magazine / Source: Behavioural Pharmacology
• MU Faculty or unit: Faculty of Medicine
• Field: Pharmacology and pharmaceutical chemistry
• Keywords: methamphetamine; behavioural sensitization; CB1 receptor downregulation
• Description: On comparison to the control animals the significantly decreased density of cannabinoid CB1 receptors on neuronal membranes of the VTA immunofluorescent detection) was found in methamphetamine treated rats.

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