Publication details

A late effect of an anthracycline therapy on 24-hour profile of blood pressure

Authors

HONZÍKOVÁ Nataša FIŠER Bohumil NOVÁKOVÁ Zuzana ZÁVODNÁ Eva HRSTKOVÁ Hana KRONTORÁDOVÁ Klára ŠŤASTNÁ Jana HONZÍK Petr

Year of publication 2008
Type Article in Proceedings
Conference 5th Conference of the European Study Group on Cardiovascular Oscillations
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords blood pressure; anthracycline; children
Description The aim of the study was nonparametric (differences in each hour, Mann-Whitney test) and parametric evaluation (the least-squares fit of the cosine curve with a period of 24 hours) of the 24-hour recordings of blood pressure (BP) in 45 patients after anticancer therapy with anthracyclines (age groups 13-15, 16-18, 19-22 years), and in 64 age-matched controls. The age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients after anthracycline therapy. This corresponded with a decreased BP in these patients in age between 19-22 years.
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