Antiarrhythmic effect of newly synthesized compound 44Bu on model of aconitine-induced arrhythmia - Compared to lidocaine

• Authors: BARTOŠOVÁ Ladislava; NOVÁK Filip; BÉBAROVÁ Markéta; FRYDRYCH Marek; BRUNCLÍK Vít; OPATŘILOVÁ Radka; KOLEVSKÁ Jana; MOKRÝ Petr; KOLLÁR Peter; STRNADOVÁ Věra; SUCHÝ Pavel
• Year of publication: 2007
• Type: Article in Periodical
• Magazine / Source: European Journal of Pharmacology
• MU Faculty or unit: Faculty of Medicine
• Field: Pharmacology and pharmaceutical chemistry
• Keywords: experimental pharmacology; aconotine mortality; lidocaine; arrhythmia; ventricular fibrillation
• Description: Compound 44Bu is a highly effective agent in suppressing aconitine-induced arrhythmias. The antiarrhythmic effect of 44Bu was significantly more evident in comparison with lidocaine, particularly in the case of its prophylactic administration.

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