Publication details
Význam signální cesty EGFR a prediktivní markery cílené léčby u karcinomů hlavy a krku
| Title in English | Significance of EGFR signaling pathways and predictive markers of targeted therpy in HNSCC |
|---|---|
| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Remedia |
| MU Faculty or unit | |
| Citation | |
| Field | ORL, ophthalmology, stomatology |
| Keywords | EGFR EGFR inhibitor predictive marker tyrosine kinase domain mutation EGFRvIII K-ras STAT3 |
| Description | Authors describe singificance of EGFR signaling pathways and possible positive and negative predictive markers in targetted therapy. As negative predictor is considred mutation K-ras, as positive amplification of gene EGFR, EGFRvIII, STAT3. |