Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs

• Authors: PLÁNKA Ladislav; NEČAS Alois; SRNEC Robert; RAUŠER Petr; STARÝ David; JANČÁŘ Josef; AMLER Evžen; FILOVÁ Eva; HLUČILOVÁ Jana; KŘEN Leoš; GÁL Petr
• Year of publication: 2009
• Type: Article in Periodical
• Magazine / Source: Physiological Research
• MU Faculty or unit: Faculty of Medicine
• Field: Traumatology and orthopaedic surgery
• Keywords: growth plate; injury; physis; limb deformity; MSCs
• Description: The MSCs which we transplanted differentiated in vivo into functional chondrocytes of the growth plate in the form of hyaline cartilage. Preventive transplantation of MSCs in our experiment prevented development of angular deformity and eliminated growth arrest of femur in physeal injuries in pigs.

Related projects

• Využití nově syntetizovaných biomateriálů v kombinaci s kmenovými buňkami v léčbě chorob, které postihují lidské tkáně derivované z mesodermu: chrupavka, kost, vazy a menisky