Association of polymorphisms of zinc metalloproteinases with clinical response to stem cell therapy

• Authors: PANOVSKÝ Roman; VAŠKŮ Anna; MELUZÍN Jaroslav; KAMÍNEK Milan; MAYER Jiří; JANOUŠEK Stanislav; KINCL Vladimír; GROCH Ladislav; NAVRÁTIL Milan
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: Herz Cardiovascular Diseases
• MU Faculty or unit: Faculty of Medicine
• Field: Cardiovascular diseases incl. cardiosurgery
• Keywords: coronary artery disease; stem cells; polymorphism; metalloproteinases
• Description: In our study, the ACE genotype II was associated with improvement of regional systolic LV function of the infarcted wall after implantations of MBMC. The detected polymorphism in matrix metalloproteinase-2 gene was not associated with clinical response to cell therapy.

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