Publication details

Biomarker discovery in low grade breast cancer: A proteomics based approach

Authors

BOUCHAL Pavel MUDROCHOVÁ Monika ROUMELIOTIS Theodoros HERNYCHOVÁ Lenka HRSTKA Roman GARBIS Spiros D. NENUTIL Rudolf VOJTĚŠEK Bořivoj

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description Traditional prognostic markers of low-grade breast cancer are currently not sufficient for precise risk-group discrimination. Our effort was thus focused on biomarker discovery in this tumor group. Three proteomics approaches were involved in complex protein analysis of tissue lysates: SELDI-TOF MS, iTRAQ-2DLC-MS/MS and 2-D SDS-PAGE. Differentially expressed proteins belong to several functional groups related to breast cancer biology and are presented and discussed on the poster.
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