Successful treatment of life-threatening Candida peritonitis in a child with abdominal non-Hodgkin lymphoma using Efungumab and amphotericin B colloid dispersion.
|Type||Article in Periodical|
|Magazine / Source||Journal of Pediatric Hematology and Oncology|
|MU Faculty or unit|
|Field||Oncology and hematology|
|Keywords||Candica peritonitis Efungumab amphotericin B colloid dispersion|
|Description||Invasive fungal infections are serious complications of cancer therapy. We present a case report of a 12-year-old boy diagnosed with abdominal non-Hodgkin lymphoma and fecal and Candida peritonitis during induction chemotherapy. The invasive mycosis was managed using a combined approach of systemic antifungal agents including efungumab and surgical interventions. Efungumab, a recombinant antibody that inhibits extracellular heat shock protein 90, was used in combination with amphotericin B colloid dispersion after the failure of standard approaches.|