Publication details
Záchovný protokol u nádorů orofaryngu
| Title in English | Organ Preservation Protocol in Oropharyngeal Cancer |
|---|---|
| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Otorinolaryngologie a foniatrie |
| MU Faculty or unit | |
| Citation | |
| Field | ORL, ophthalmology, stomatology |
| Keywords | oropharynx; cancer; organ preservation protocol; surgery; surfoval; quality of life |
| Description | We retrospectively reviewed data from 190 patients with resectable stage III or IV oropharyngeal squamous cell carcinoma treated in our hospital from 2001 through 2008. The primary tumor was surgically treated in 123 patients, in 67 patients non-surgically. Out of total 67 OPP patients, the treatment was completed by 62 (93%). 47 patients (70%) achieved complete response. 41 patients (61%) were healed by conservative treatment only without any surgery (organ preservation). The remainder, 6 patients, underwent salvage surgery. The survival rates (OAS, DSS, DFI) in the surgery group exceeded that of the organ preserving group statistically. No significant difference in quality of life was demonstrated between both categories on account of high toxicity and adverse effects of chemoradiation. |