Publication details

In Silico Engineering of Proteins that Recognize Small Molecules

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MISHRA Sushil Kumar DEMO Gabriel KOČA Jaroslav WIMMEROVÁ Michaela

Year of publication 2012
Type Chapter of a book
MU Faculty or unit

Central European Institute of Technology

Description Protein engineering is a rapidly evolving discipline, with much research currently focused on understanding the catalysis, specificity, stability, and folding of proteins, structure-function relationships and protein design principles. Engineered proteins are now successfully being used in biotechnology and in therapeutic settings. Advances in technology and genetic and chemical techniques have enabled a competitive edge in developing improved protein and peptide based therapeutics with reduced immunogenicity, improved safety and greater effectiveness.
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