Informace o projektu
Tetrapyrrole-Flavonol Hybrids as Efficient NIR photoCORMs
- Kód projektu
- MUNI/IGA/1217/2020
- Období řešení
- 1/2021 - 12/2021
- Investor / Programový rámec / typ projektu
-
Masarykova univerzita
- Interní grantová agentura MU
- Fakulta / Pracoviště MU
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Přírodovědecká fakulta
- Andrea Ramundo, Ph.D.
Carbon monoxide, despite its toxicity, is a signaling molecule with anti-inflammatory and cell-protective properties, with possible clinical applications. Because a controlled releasing mechanism at the cellular level is needed, light-activated CO-delivering molecules can provide a high spatial and temporal precision, allowing the drug to be delivered only into the targeted tissues. One of these molecules, with low toxicity and near-IR absorption, will be designed and studied within this project