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Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis

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JANČAŘÍKOVÁ Gita HOUSER Josef DOBEŠ Pavel HYRŠL Pavel WIMMEROVÁ Michaela

Rok publikování 2017
Druh Další prezentace na konferencích
Fakulta / Pracoviště MU

Přírodovědecká fakulta

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Popis Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity.
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