Informace o publikaci

Subtype definition of vascular parkinsonism

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REKTOR Ivan BOHNEN N.I. KORCZYN A.D.

Rok publikování 2018
Druh Článek v odborném periodiku
Časopis / Zdroj PARKINSONISM & RELATED DISORDERS
Fakulta / Pracoviště MU

Středoevropský technologický institut

Citace
Doi http://dx.doi.org/10.1016/j.parkreldis.2018.03.005
Klíčová slova OLDER-ADULTS; DISEASE; DENERVATION; SIGNS
Popis We thank Dr. Levin for expressing interest in our work. Dr. Levin applies a traditional clinico-anatomic perspective to interpret our proposed criteria, pointing out that our criteria do not exclusively require that vascular lesions be located within specific topographic regions, such as the nigrostriatal and striato-thalamo-cortical pathways. At the same time, Dr. Levin notes the often observed clinical scenario in which patients with extensive and confluent vascular lesions on brain MRI scans may be fully asymptomatic motor-wise despite the fact that some of these lesions may be located in regions of critical motor circuitry. This scenario shows that factors other than the geographic location of vascular lesions in the brain may play a role in the pathogenesis of vascular parkinsonism (VaP).

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