Informace o publikaci

Extramedullary disease in multiple myeloma - controversies and future directions

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ŠEVČÍKOVÁ Sabina MINARIK Jiri STORK Martin JELINEK Tomas POUR Ludek HAJEK Roman

Rok publikování 2019
Druh Článek v odborném periodiku
Časopis / Zdroj BLOOD REVIEWS
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www http://dx.doi.org/10.1016/j.blre.2019.04.002
Doi http://dx.doi.org/10.1016/j.blre.2019.04.002
Klíčová slova Multiple myeloma; Extramedullary disease; Treatment; Resistance; Biomarker
Popis Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.
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