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The Use of Dalbavancin with a Dermal Substitute Application - a Case Report



Rok publikování 2021
Druh Článek v odborném periodiku
Časopis / Zdroj Acta chirurgiae plasticae
Fakulta / Pracoviště MU

Lékařská fakulta

Klíčová slova Dalbavancin; Dermal Substitute Application
Popis The application of dermal substitutes is currently becoming increasingly important in the local therapy of a wide range of acute and chronic full-thickness wounds [1]. Dermal substitutes provide two basic functions of the cutaneous dermal layer: control of pain and scarring. They act as matrices or scaffolds, promote new tissue growth and enhance wound healing. The control of the whole process of scarring after the application of dermal substitutes also leads to a reduction in the risk of pathological scars – hypertrophic or keloid scars [2]. One of the biggest challenges associated with the application of dermal substitutes in general is the risk of developing infectious complications – skin and soft tissue infections (SSTIs). A specific subunit of SSTIs, acute bacterial skin and soft tissue infections (ABSSTIs), is defined as a SSTI with a proven bacterial causative agent together with a minimum affected area of 75 cm2 [3]. In this case report, we present a complicated case of multiple SSTIs in a young woman at high risk of developing phlebitis and significant intolerance to a variety of antimicrobials, in which we managed to control the dramatic picture with dalbavancin.
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