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Allergic bronchopulmonary candidiasis: A review of the literature and a case report

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ŠČUREK Martin POKOJOVÁ Eva DOUBKOVÁ Martina BRAT Kristián

Rok publikování 2022
Druh Článek v odborném periodiku
Časopis / Zdroj BMC Pulmonary Medicine
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-022-01921-3
Doi http://dx.doi.org/10.1186/s12890-022-01921-3
Klíčová slova Allergic bronchopulmonary candidiasis; Allergic bronchopulmonary mycosis; Candida albicans; Pulmonary infiltrates
Popis Background Allergic bronchopulmonary candidiasis (ABPC) is an uncommon clinical syndrome associated with immune hypersensitivity to Candida species. Case presentation The case presentation describes a 58-year-old man with acute respiratory failure and bilateral lung infiltrates. Due to high inflammatory markers and a chest X-ray indicating lung infiltration, he was initially treated for pneumonia with combined antibiotics. Despite comprehensive treatment at the ICU, the patient’s clinical status deteriorated rapidly, and further investigations provided a rare diagnosis of ABPC. After several days of combined corticosteroid and antifungal therapy, we observed rapid clinical improvement and subsequent resolution of the pulmonary infiltrates. Conclusion This case report presented a rare case of ABPC mimicking bilateral pneumonia and acute respiratory failure. Our case highlighted the importance of prompt corticosteroid and antifungal treatment initiation as it resulted in rapid clinical improvement and a near complete reversal of the bilateral lung infiltrates.

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