Registry-based analysis of Icatibant and C1-inhibitor use in treatment of laryngeal attacks of hereditary angioedema

• Autoři: HAKL Roman; KUKLÍNEK Pavel; SOBOTKOVA Marta; KRCMOVA Irena; KRALICKOVA Pavlina; VACHOVA Martina; HANZLIKOVA Jana; NOVACKOVA Martina; SVOBODA Michal; KOVÁČOVÁ Ingrid; LITZMAN Jiří
• Rok publikování: 2022
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: CLINICAL AND EXPERIMENTAL ALLERGY
• Fakulta / Pracoviště MU: Lékařská fakulta
• www: https://onlinelibrary.wiley.com/doi/10.1111/cea.14182
• Doi: http://dx.doi.org/10.1111/cea.14182
• Klíčová slova: Icatibant; C1-inhibitor; hereditary angioedema; laryngeal attacks
• Popis: Hereditary angioedema (HAE) is a rare condition which manifests as repeated episodes of localized subcutaneous or submucosal oedema. Oedemas involving the upper airways carry the risk of asphyxiation and death. The aim of this study was to present our clinical experience of icatibant and C1 inhibitor use for treating HAE-1/2 laryngeal attacks (LA). To our knowledge, this is the first direct comparison of these treatment approaches for LA.