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Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.

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MIHALČIN Matúš HUSOVÁ Libuše VAŠÍČKOVÁ Petra BENA Marcel HUSA Petr

Rok publikování 2022
Druh Článek v odborném periodiku
Časopis / Zdroj Archives of Medical Science
Fakulta / Pracoviště MU

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Citace
www https://www.archivesofmedicalscience.com/Hepatitis-E-epidemiology-and-clinical-course-in-the-largest-cohort-in-the-Czech-Republic,152338,0,2.html
Doi http://dx.doi.org/10.5114/aoms/152338
Klíčová slova therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis
Popis Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Material and methods: The retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.

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