Informace o publikaci
The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia
| Autoři | |
|---|---|
| Rok publikování | 1999 |
| Druh | Článek ve sborníku |
| Konference | Cells |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | acute myeloid leukemia |
| Popis | Eighty percent of children with AML show clonal chromosomal aberrations on cytogenetic examination. The most frequent aberrations rexognised in AML are t(8;21), t(15;17), inv(16) and 11q23. These aberrations comprise 10-45% of all AML cases in choldren. Recently, the molecular genetic examination of these specific changes is available with the sensitivity of finding one leukemic cell bearing the translocation in between 1 million of normal cells. |
| Související projekty: |