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Layer-specific residual strains in human carotid arteries revealed under layer separation

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HRUBANOVA Anna LISICKY Ondrej SOCHOR Ondrej BEDNAŘÍK Zdeněk JOUKAL Marek BURSA Jiri

Rok publikování 2025
Druh Článek v odborném periodiku
Časopis / Zdroj Plos one
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0308434
Doi https://doi.org/10.1371/journal.pone.0308434
Klíčová slova esidual strain; carotid artery; arterial wall layers; biomechanics; layer separation
Popis Residual stresses are considered as a significant factor influencing the stress-states in arteries. These stresses are typically observed through opening angle of a radially cut artery segment, often regarded as a primary descriptor of their stress-free state. However, the experimental evidence regarding the stress-free states of different artery layers is scarce. In this study, two experimental protocols, each employing different layer-separating sequences, were performed on 17 human common carotid arteries; the differences between both protocols were found statistically insignificant. While the media exhibited opening behaviour (reduced curvature), a contrasting trend was observed for the adventitia curvature, indicating its closing behaviour. In addition to the different bending effect, length changes of both layers after separation were observed, namely shortening of the adventitia and elongation of the media. The results point out that not all the residual stresses are released after a radial cut but a significant portion of them is released only after the layer separation. Considering the different mechanical properties of layers, this may significantly change the stress distribution in arterial wall and should be considered in its biomechanical models.
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