Informace o publikaci
Feasibility of implementing ESPEN/EASO consensus criteria for sarcopenic obesity assessment in bariatric surgery: A dual-modality imaging pilot study
| Autoři | |
|---|---|
| Rok publikování | 2025 |
| Druh | Recenzovaný odborný článek |
| Časopis / Zdroj | Clinical Nutrition ESPEN |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://www.sciencedirect.com/science/article/pii/S2405457725030025?pes=vor&utm_source=clarivate&getft_integrator=clarivate |
| Doi | https://doi.org/10.1016/j.clnesp.2025.11.009 |
| Klíčová slova | Sarcopenic obesity; Bariatric surgery; ESPEN/EASO consensus; Dual-modality imaging; Feasibility study; Pilot trial methodology |
| Popis | Background: The heterogeneous diagnostic methods for sarcopenic obesity lack standardization across clinical practice. The 2022 ESPEN/EASO consensus established standardized diagnostic criteria emphasizing weight-adjusted muscle mass indices, yet implementation feasibility in bariatric surgery populations remains unexplored. The absence of validated cutoff values for Class III obesity and limited evidence on dual-modality assessment protocols represent critical barriers to clinical implementation. Objective: This pilot study objectively assessed the implementation of ESPEN/EASO consensus criteria using dual-modality DXA and MRI assessment in women undergoing sleeve gastrectomy, with primary focus on protocol completion rates, technical precision, and preliminary evaluation of weight-adjusted diagnostic indices. Methods: Following CONSORT 2010 pilot trial extension guidelines, this feasibility study analyzed eleven women (age 41.3 f 7.9 years (95 % CI: 36.6-46.0 years), 41.0 f 5.0 kg/m2 (95 % CI: 38.0-44.0 kg/ m2) undergoing laparoscopic sleeve gastrectomy. Primary feasibility outcomes included dual-modality assessment completion rates, MRI segmentation algorithm performance, and protocol adherence. Secondary outcomes encompassed preliminary body composition changes and ASM/weight diagnostic utility evaluation using ESPEN/EASO recommended cutoffs. Results: Dual-modality assessment achieved 100 % completion rates with excellent technical precision (MRI segmentation Dice coefficient: 0.95 f 0.01 for muscle, 0.95 f 0.03 for adipose tissue). Protocol adherence was optimal with all participants completing scheduled assessments. Preliminary body composition analysis demonstrated substantial weight reduction of 29.4 f 25.3 kg (95 % CI: 14.4-44.4 kg) at six months. ASM/weight ratios showed potential diagnostic utility, though wide confidence intervals reflect substantial uncertainty inherent in small sample analysis. Conclusions: Implementation of ESPEN/EASO consensus criteria demonstrates 100 % protocol completion rates and MRI segmentation precision with Dice coefficients of 0.95 f 0.01 for muscle and 0.95 +/- 0.03 for adipose tissue in bariatric surgery populations. This pilot study establishes the methodological foundation and demonstrates feasibility for larger-scale validation studies to develop obesity-specific diagnostic thresholds and optimize sarcopenic obesity assessment protocols in bariatric medicine. (c) 2025 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. |