Informace o publikaci

Mapping the human chemical exposome for public health

Autoři	DAVID Arthur LENNON Sarah MERCIER Fabien BOUHLEL Jihene CHAKER Jade APPENZELLER Brice M. R. AUDOUZE Karine AYENI Kolawole I. BAILLY-CHOURIBERRY Ludovic SOULEIMAN El Balkhi BAROUKI Robert BELOVA Lidia BENMARHNIA Tarik BONNEFILLE Benilde BESSONNEAU Vincent BONVALLOT Nathalie BOUCHART Valerie BOUVIER-CAPELY Celine BUISSON Corinne BURY Daniel COVACI Adrian COUMOUL Xavier DEBRAUWER Laurent DELEPEE Raphael DENYS Sebastien DEREUMEAUX Clementine FEUERSTEIN Max L. FILLOL Clemence GAGO-FERRERO Pablo GARCIA Patrice GICQUEL Thomas GIL-SOLSONA Ruben GROVA Nathalie HABCHI Baninia HERNANDES Vinicius V. IGLESIAS-GONZALEZ Alba JAMIN Emilien L. KOCH Holger M. LEFEVRE-ARBOGAST Sophie LINDH Christian LOUYER Mari-Vorgan MACHEKA Linda R MARTIN Jonathan W. MARQUES Montse MOL Hans NDAW Sophie OLEKO Amivi PAPAZIAN Stefano PŘIBYLOVÁ Petra PRICE Elliott James SCHYMANSKI Emma L. THIELE Solveig WARTH Benedikt ZEMAN Florence BLANC Etienne ANTIGNAC Jean-Philippe LE BIZEC Bruno SAMSON Michel
Rok publikování	2026
Druh	Recenzovaný odborný článek
Časopis / Zdroj	Nature Medicine
Fakulta / Pracoviště MU	Přírodovědecká fakulta
Citace
www	https://www.nature.com/articles/s41591-026-04289-7
Doi	https://doi.org/10.1038/s41591-026-04289-7
Klíčová slova	Chemical exposome; Human biomonitoring; Exposomics; High-resolution mass spectrometry; Chemical mixture toxicity; Environmental health
Popis	This article introduces the Human Internal Chemical Exposome Atlas (iChemAtlas), a collaborative initiative aimed at systematically mapping the human internal chemical exposome using scalable multi-platform mass spectrometry. The framework integrates targeted and non-targeted approaches to characterize exogenous chemicals and their biotransformation products in human biospecimens. By generating an open and harmonized resource for chemical exposure profiling, the initiative seeks to advance biomonitoring, mixture toxicity assessment, and public health research, while supporting future applications in exposure science and precision medicine.
Související projekty:	CETOCOEN Excellence CETOCOEN Excellence Environmental Exposure Assessment Research Infrastructure Preparatory Phase Project Výzkumná infrastruktura RECETOX