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Increased markers of oxidative stress in plasma of patients with chronic pancreatitis

Název česky Zvýšený ukazatel oxidativního stresu v plazmě pacientů s chronickou pankreatitidou
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PODBORSKÁ Martina ADAMCOVÁ Arona TRNA Jan DÍTĚ Petr LOJEK Antonín KUBALA Lukáš

Rok publikování 2009
Druh Článek v odborném periodiku
Časopis / Zdroj Neuroendocrinology Letters
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Ostatní obory vnitřního lékařství
Klíčová slova chronic panreatitis - lipid peroxidation - nitrites - total antioxidant capacity
Popis Chronic pancreatitis (CP) is a heterogeneous disease defined as chronic inflammatory changes of the pancreatic tissue caused by variety of aetiologies. Oxidative stress accompanying the inflammatory processes has been suggested as an important factor contributing to CP development. The aim of this study was to determine levels of lipid peroxidation products malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE),together with nitrites and the total antioxidant capacity in the plasme of patients with CP and control subjects.