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Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde

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PĚNČÍKOVÁ Kristýna URBANOVÁ Jana TÁBORSKÁ Eva

Rok publikování 2012
Druh Konferenční abstrakty
Fakulta / Pracoviště MU

Lékařská fakulta

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Přiložené soubory
Popis For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.
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