Mgr. Lenka Dostálová
Research specialist - PhD student, Michal Šmída Research Group
Office: bldg. E35/142
Kamenice 753/5
625 00 Brno
Phone: | +420 549 49 5875 |
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E‑mail: |
Total number of publications: 16
2022
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Combined drug and CRISPR/CAS9 screening reveals specific targets for SF3B1- and NOTCH1- mutated CLL cells.
Year: 2022, type: Conference abstract
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Chasing the epigenetic landscape to enhance CAR-T cell activity by preventing CD19 antigen escape in relapsed models.
Year: 2022, type: Conference abstract
2021
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CD19 promoter hypermethylation as means of antigen-negative escape to CART-19 therapy.
Year: 2021, type: Conference abstract
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Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro
Journal for ImmunoTherapy of Cancer, year: 2021, volume: 9, edition: 8, DOI
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In vivo antigen-negative escape to CART-19 caused by CD19 promotor hypermethylation.
Year: 2021, type: Conference abstract
2020
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Genome-wide CRISPR/Cas9 screening reveals novel target genes, whose inactivation is able to upregulate surface expression of immunotherapy target CD20
Year: 2020, type: Conference abstract