Project information

Project information
Endoscopic variceal band ligation in comparison wirh betablockers in prophylaxis of first variceal bleeding in patients with liver cirrhosis

Project Identification
NK6947
Project Period
1/2002 - 12/2004
Investor / Pogramme / Project type
Ministry of Health of the CR
MU Faculty or unit
Faculty of Medicine
Keywords
esophageal varices;bleeding prohylaxis;endoscopic ligation;propranolol;liver cirrhosis
Cooperating Organization
Charles University
Palacký University, Olomouc
Institute of Clinical and Experimental Medicine Prague
General Teaching Hospital Praha

We conducted a prospective, multicentric, randomised, controlled trial to compare the efficacy and safety of propranolol and endoscopic variceal band ligation for the primary prophylaxis of variceal bleeding. Only patients with high-risk esophageal varices will participate in this study with principal end point to decrese the probability of life-threatening bleeding from esophageal varices.

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