Project information
Project information
Mutační analýza primitivních buněčných populací u chronické myeloidní leukémie: za hranicí BCR-ABL1
- Project Identification
- 17-30397A (kod CEP: NV17-30397A)
- Project Period
- 4/2017 - 12/2020
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- Ministry of Health Research Programme 2015 - 2022
- MU Faculty or unit
- Central European Institute of Technology
- Cooperating Organization
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University Hospital Brno-Bohunice
- Responsible person prof. MUDr. Zdeněk Ráčil, Ph.D.
Mutační analýza primitivních buněčných populací u chronické myeloidní leukémie: za hranicí BCR-ABL1
Publications
Total number of publications: 9
2021
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Digital PCR can provide improved BCR-ABL1 detection in chronic myeloid leukemia patients in deep molecular response and sensitivity of standard quantitative methods using EAC assays
Practical Laboratory Medicine, year: 2021, volume: 25, edition: MAY, DOI
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Hierarchical distribution of somatic variants in newly diagnosed chronic myeloid leukaemia at diagnosis and early follow-up
British journal of haematology, year: 2021, volume: 194, edition: 3, DOI
2020
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Analysis of serum lipids, cardiovascular risk, and indication for statin use during nilotinib and imatinib therapy in de novo CML patients ? results from real-life prospective study
LEUKEMIA & LYMPHOMA, year: 2020, volume: 61, edition: 2, DOI
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Novel Illumina-based next generation sequencing approach with one-round amplification provides early and reliable detection of BCR-ABL1 kinase domain mutations in chronic myeloid leukemia
British journal of haematology, year: 2020, volume: 189, edition: 3, DOI
2019
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Analysis of gene expression in CD26+ CML leukemic stem cell population.
Year: 2019, type: Conference abstract
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Gene expression profiling of CD26+ leukemic stem cell population from CML patients.
Year: 2019, type: Conference abstract
2018
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Insulin resistance is an underlying mechanism of impaired glucose metabolism during nilotinib therapy
American Journal of Hematology, year: 2018, volume: 93, edition: 10, DOI
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Ultrasensitive detection of TKI resistant mutations using Illumina NGS in chronic myeloid leukemia patients.
Year: 2018, type: Conference abstract
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Ultra-sensitive detection of tyrosine kinase inhibitor resistant mutations in chronic myeloid leukemia patients using Miseq Illumina next generation sequencing platform
Year: 2018, type: Conference abstract