Publication details

Neoadjuvant chemotherapy for primary advanced ovarian cancer

Authors

TRHLÍK Martin SOUMAROVÁ Renata BARTOŠ Pavel KOLÁČEK Jan HOROVÁ Ivanka TĚŽKÁ Markéta

Year of publication 2013
Type Article in Periodical
Magazine / Source Biomedical Papers
MU Faculty or unit

Faculty of Science

Citation
Web http://biomed.papers.upol.cz/artkey/pri-990000-0600_VOLUME_157_Supplement_2.php
Field Applied statistics, operation research
Keywords neoadjuvant chemotherapy; ovarian cancer
Description Primary debulking surgery before adjuvant chemotherapy (ACT) is the standard of care for patients with advanced ovarian cancer but neoadjuvant CT (NACT) is an alternative therapeutic approach in stage IIIC or IV disease. We evaluated our patients with NACT and its influence on radicality of surgery and overall survival (OS). We evaluated 138 women treated for advanced ovarian cancer of stage FIGO IIIC-IV not suitable for primary debulking surgery (PDS) because of unresectable tumor or poor performance status. All women underwent laparoscopic evaluation – confirming inoperable advanced ovarian cancer of stage IIIC-IV. After the NACT of 3-4 series was provided this was followed by laparoscopic reevaluation.

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