Publication details

The variable clinical course of peripartum cardiomyopathy

Authors

KREJČÍ Jan HUDE Petr ŠPINAROVÁ Lenka ŽAMPACHOVÁ Víta SIROTKOVÁ Alžběta FREIBERGER Tomáš NEMCOVA Eva VÍTOVEC Jiří

Year of publication 2014
Type Article in Periodical
Magazine / Source Biomedical Papers
MU Faculty or unit

Faculty of Medicine

Citation
Web http://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-0413#.UuD56LRNxQI
Doi http://dx.doi.org/10.5507/bp.2012.080
Field Cardiovascular diseases incl. cardiosurgery
Keywords peripartum cardiomyopathy; myocarditis; echocardiography; endomyocardial biopsy; therapy
Description Background: In Europe, peripartum cardiomyopathy (PPCM) is a rare disorder, often difficult to diagnose and it has a variable clinical course. The aim of this report was to describe and discuss the individual variability of this disorder and its management. Patients and Methods: Three cases of PPCM manifesting as severe heart failure are compared. Common was the presence of myocardial inflammation detected by endomyocardial biopsy. Different were treatment methods and clinical course. Modern therapeutic concepts such as immunosuppressive therapy and bromocriptin administration are discussed, as well as non-pharmacological approaches. Conclusion: In the differential diagnostics of dyspnea associated with pregnancy and childbirth, PPCM should be considered. The potentially severe course of the disease requires hospitalization with the possibility of comprehensive heart failure treatment, including non-pharmacological approaches such as device therapy and heart transplantation.

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